Development and evaluation of an optical fibre-based helium-neon laser irradiation system for tissue regeneration: A pilot study |
| |
| Authors: | Vijendra Prabhu B S Satish Rao B Nageshwara Rao B Kiran Aithal B Satish Shenoy and K K Mahato |
| |
| Institution: | (1) Entest BioMedical, San Diego, CA, USA;(2) Georgetown Dermatology, Washington, DC, USA;(3) Cromos Pharma Services, Longview, WA, USA;(4) Center for the Study of Natural Oncology, Del Mar, CA, USA;(5) Department of Hematology and Medical Oncology, St Francis Hospital and Medical Center, Hartford, CT, USA;(6) Moores Cancer Center, University of California San Diego, San Diego, CA, USA;(7) Department of Cardiothoracic Surgery, University of Utah, Salt Lake City, UT, USA |
| |
| Abstract: | Low level laser therapy is being extensively used to treat various medical ailments including wound healing. In the present
study, an optical fibre-based helium-neon (He-Ne) laser irradiation system was designed, developed and evaluated for optimum
tissue repair on mice excision wounds. Circular wounds of 15 mm diameter were created on the dorsum of animals and single
exposure of uniformly distributed laser beam was administered at 1, 2 and 3 J/cm2 to the respective test groups with suitable controls. Progression of healing was monitored by measuring wound contraction
and mean healing time. Significant reduction in wound size and mean healing time (p <0.001) were observed in the test groups for the laser dose of 2 J/cm2 compared to the unilluminated controls, suggesting the suitability of this dose. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
