A convenient route to 2,6-dialkyl-2,3-dihydro-4H-pyran-4-ones via oxidative cleavage of protected 1-(2-oxoalkyl)-cyclopropanols. Synthesis of (±)-hepialone and its natural congener |
| |
| Authors: | Dmitry A Astashko Vladimir I Tyvorskii |
| |
| Institution: | Department of Organic Chemistry, Belarusian State University, Nezalezhnasti Avenue, 4, 220030 Minsk, Belarus |
| |
| Abstract: | An efficient strategy for the synthesis of 2,6-dialkyl-2,3-dihydro-4H-pyran-4-ones has been developed, the key steps of which are oxidative cleavage of the three-membered rings of 1-(2-oxoalkyl)-cyclopropanols and acid-promoted cyclization of the resulting β-hydroxyketones. |
| |
| Keywords: | Cyclopropanols Oxidation β-Hydroxyketones Pheromones |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
