An efficient diastereoselective synthesis of spiro pyrido[2,1-b][1,3]oxazines via a novel pyridine-based three-component reaction |
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| Authors: | Abbas Ali Esmaeili Hamid VesalipoorRahele Hosseinabadi Alireza Fakhari ZavarehMohammad Ali Naseri Ebrahim Ghiamati |
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| Affiliation: | a Chemistry Department,University of Birjand, Birjand, PO Box 97175/615, Iran
b Chemistry Department, Faculty of Sciences, Shahid Beheshti University, Tehran, Iran |
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| Abstract: | The zwitterions generated from pyridine and dialkyl acetylenedicarboxylate (DAAD) reacted with benzofuran-2,3-diones to form highly substituted spiro pyrido[2,1-b][1,3]oxazines in good to high yields without using a catalyst. |
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| Keywords: | Benzofuran-2,3-dione Dialkyl acetylenedicarboxylates Pyridine Spiro pyrido[2,1-b][1,3]oxazine Multicomponent reactions |
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