| 超临界流体输运技术在缓／控释药物制备中的应用 |
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| 引用本文： | 倪敏,徐琴琴,徐刚,王恩俊,银建中.超临界流体输运技术在缓／控释药物制备中的应用[J].化学进展,2011(8):1611-1617. |
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| 作者姓名： | 倪敏 徐琴琴 徐刚 王恩俊 银建中 |
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| 作者单位： | 大连理工大学化工机械学院; |
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| 基金项目： | 国家自然科学基金项目(No.20976028)资助 |
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| 摘 要： | 缓／控释药物制剂作为一种新药剂是药学研究的热点。本文对近年来超临界流体技术在缓／控释药物系统制备中的研究成果进行了回顾和总结，重点对以超临界流体为溶剂、无机介孔材料为载体制备缓／控释药物系统的方法进行了阐述和评价，内容包括：技术原理、工艺流程、主要影响因素、药效试验、与传统方法比较等。分析了各种工艺流程的优缺点，并指出...
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| 关 键 词： | 超临界流体 输运技术 浸渍与沉积 缓/控释药物 释放 |
Applications of Supercritical Fluid Transport Technology in Preparation of Controlled-Release Drug Delivery Systems |
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| Ni Min Xu Qinqin Xu Gang Wang Enjun Yin Jianzhong.Applications of Supercritical Fluid Transport Technology in Preparation of Controlled-Release Drug Delivery Systems[J].Progress in Chemistry,2011(8):1611-1617. |
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| Authors: | Ni Min Xu Qinqin Xu Gang Wang Enjun Yin Jianzhong |
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| Institution: | Ni Min Xu Qinqin Xu Gang Wang Enjun Yin Jianzhong (School of Chemical Machinery,Dalian University of Technology,Dalian 116024,China) |
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| Abstract: | Among the research of new pharmaceutic dosage forms,controlled-release drug delivery system is a very important issue nowdays.In this field,processes using supercritical fluid technology are mostly clean process leading to clean products.Meanwhile,inorganic porous materials are emerging as a new category of host/guest systems due to some interesting features such as their biological stability and their drug-releasing properties.This review summarizes the applications of supercritical fluid transport technol... |
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| Keywords: | supercritical fluid transport technology impregnation and deposition controlled-release drug release |
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