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| Ru(bpy)2dppx2+与核酸作用的光谱研究 | |
| 引用本文： | Wu M,Song G,Ling L,He Z,Zeng Y. Ru(bpy)2dppx2+与核酸作用的光谱研究[J]. 光谱学与光谱分析, 2000, 20(4): 575-576 |
| 作者姓名： | Wu M Song G Ling L He Z Zeng Y |
| 作者单位： | 1. 湖北咸宁师范学院化学系 2. 湖北大学分析测试中心,430062,武汉 3. 武汉大学化学学院,430072,武汉 |
| 摘 要： | 合成７,８－二甲基二联吡啶并（３,２,ａ：２’,３’,ｃ）吩嗪,简称ｄｐｐｘ,并合成了Ｒｒ（ｂｐｙ）２ｄｐｐｘ＾２＋混配物,研究了混配物与ＤＮＡ作用的紫外－可见光谱与荧光光谱。在ｐＨ９．５时ＤＮＡ能使混配物的紫外可见光谱发生明显的减色效应,荧光光谱在５９９ｎｍ处（λｅｘ＝４７１ｎｍ）产生新的荧光峰,探讨了反应的机理。 |
| 关 键 词： | 钌配合物 荧光光谱 紫外－可见光谱 DNA 结构 |
Synthesis and DNA binding studies of Ruthenium complexes by spectra |
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| Wu M,Song G,Ling L,He Z,Zeng Y. Synthesis and DNA binding studies of Ruthenium complexes by spectra[J]. Spectroscopy and Spectral Analysis, 2000, 20(4): 575-576 | |
| Authors: | Wu M Song G Ling L He Z Zeng Y |
| Affiliation: | Analysis and Testing Center, Hubei University, 430062 Wuhan. |
| Abstract: | New Complexes Ru(bpy)2dppx2+ were synthesized. The binding of Ru(bpy)2dppx2+ to calf thymus DNA has been investigated by using electronic absorption and fluorescence spectra. The intercalation mode was proved to exist. The DNA leads to a dramatic enhancement of the photoluminescence of the drug at 599 nm (lambda ex = 471 nm) and absorption hypochromic effect and red shift. It was obvious that Ruthenium complexes may be used at a good DNA probe. |
| Keywords: | Ruthenium complexes Calf thymus DNA Fluorescence and absorption spectra |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ | |