Synthesis and antibacterial activity of some imidazo[1,2-a]pyrimidine derivatives. |
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| Authors: | Y Rival G Grassy G Michel |
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| Institution: | Laboratoire de Chimie Organique, Faculté de Pharmacie, Illkirch, France. |
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| Abstract: | A series of 75 imidazo1,2-a]pyrimidine derivatives were synthesized. The "in vitro" antibacterial activity of these compounds and their corresponding alpha-bromoketones against a variety of gram (+), gram (-) bacteria and Mycobacterium species is reported. Some of the prepared derivatives exhibited potent antimicrobial activity. |
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