| Synthesis and antitumor activity of derivatives of 23-hydroxybetulinic acid |
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| 引用本文： | Jin Pei Zhou Dan Li Xiao Ming Wu Wen Cai Ye Lu Yong Zhang. Synthesis and antitumor activity of derivatives of 23-hydroxybetulinic acid[J]. 中国化学快报, 2007, 18(10): 1195-1198. DOI: 10.1016/j.cclet.2007.07.017 |
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| 作者姓名： | Jin Pei Zhou Dan Li Xiao Ming Wu Wen Cai Ye Lu Yong Zhang |
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| 作者单位： | a，* |
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| 摘 要： | A series of natural product 23-hydroxybetulinic acid derivatives were prepared.In the preparation of mono-O-benzoyl ester derivative,it was observed that benzoyl group migrated from 3-O-to 23-O-position during the detritylation.
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| 关 键 词： | 三萜系化合物 酸性物质 抗癌作用 合成方法 |
| 收稿时间： | 2007-04-13 |
| 修稿时间： | 2007-04-13 |
Synthesis and antitumor activity of derivatives of 23-hydroxybetulinic acid |
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| Jin Pei Zhou,Dan Li,Xiao Ming Wu,Wen Cai Ye,Lu Yong Zhang. Synthesis and antitumor activity of derivatives of 23-hydroxybetulinic acid[J]. Chinese Chemical Letters, 2007, 18(10): 1195-1198. DOI: 10.1016/j.cclet.2007.07.017 |
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| Authors: | Jin Pei Zhou Dan Li Xiao Ming Wu Wen Cai Ye Lu Yong Zhang |
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| Affiliation: | 1. Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China;2. Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, China;3. National Drug Screening Center, China Pharmaceutical University, Nanjing 210038, China |
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| Abstract: | A series of natural product 23-hydroxybetulinic acid derivatives were prepared.In the preparation of mono-O-benzoyl ester derivative,it was observed that benzoyl group migrated from 3-O-to 23-O-position during the detritylation. |
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| Keywords: | 23-Hydroxybetulinic acid Triterpenoid Antitumor Synthesis |
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