| 分子印迹基质固相分散-超高效液相色谱法测定儿童玩具中双酚A |
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| 引用本文： | 徐靖,刘娟,金江岚.分子印迹基质固相分散-超高效液相色谱法测定儿童玩具中双酚A[J].理化检验(化学分册),2011(6). |
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| 作者姓名： | 徐靖 刘娟 金江岚 |
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| 作者单位： | 国家日用小商品质量监督检验中心;义乌市林业局;义乌市产品质量监督检验所; |
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| 基金项目： | 浙江省分析测试项目(2009F70051); 浙江省质监系统定向委托科研项目(20080503) |
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| 摘 要： | 以双酚A为模板分子,4-乙烯基吡啶为功能单体合成了双酚A分子印迹聚合物(BPAMIP),作为基质固相分散吸附剂,用于提取儿童玩具中双酚A。样品溶液均匀地分散在BPA-MIP中,风干后用二氯甲烷淋洗,然后用甲醇(35+65)溶液作洗脱剂将双酚A洗下,收集洗出液供高效液相色谱测定。结果表明:聚合物对印迹分子具有很好的亲和性和特异选择性。方法的线性范围为1.5～100.0mg·L~(-1),检出限(3S/N)为0.12mg·L~(-1)。在5个浓度水平下做加标回收试验,回收率在94.9%～99.1%之间,相对标准偏差(n=6)在1.2%～3.4%之间。
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| 关 键 词： | 超高效液相色谱 分子印迹聚合物 基质固相分散 双酚A 儿童玩具 |
UHPLC Determination of Bisphenol A in Children's Toys with Molecularlv Imprinted Matrix Solid Phase Dispersion |
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| XU Jing,LIU Juan,JIN Jiang-lan.UHPLC Determination of Bisphenol A in Children's Toys with Molecularlv Imprinted Matrix Solid Phase Dispersion[J].Physical Testing and Chemical Analysis Part B:Chemical Analgsis,2011(6). |
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| Authors: | XU Jing LIU Juan JIN Jiang-lan |
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| Institution: | XU Jing~1,LIU Juan~2,JIN Jiang-lan~3 (1.State Center of Quality Supervision and Inspection for Petty Commodities,Yiwu 322000,China,2.Yiwu Municipal Bureau of Forestry,3.Yiwu Municipal Institute for Supervision and Inspection of Product Quality,China) |
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| Abstract: | The molecularly imprinted polymer(MIP)of bisphenol A(BPA)was synthesized with BPA as template molecule and 4-vinylpyridine as functional monomer,and it was used to extract BPA as adsorbent of matrix solid phase dispersion from children's toys.The sample solution was dispersed in BPA-MIP,and rinsed with CH_2Cl_2 after drying.Then BPA on the imprinted polymer was eluted with CH_3OH-H_2O(35 + 65)mixture,which was collected and used for UHPLC determination.It was found that the imprinted polymer had good affini... |
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| Keywords: | UHPLC Molecularly imprinted polymer Matrix solid phase dispersion Bisphenol A Children's toys |
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