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Synthetic access to arsenic-containing phosphatidylcholines
Authors:Nikolaus Guttenberger  Ronald A Glabonjat  Sebastian Tassoti  Kevin A Francesconi
Institution:Institute of Chemistry, NAWI Graz, University of Graz, Universitaetsplatz 1, 8010 Graz, Austria
Abstract:We wish to disclose the first synthesis of 1-O-hexadecanoyl-2-O-((15-(dimethylarsinoyl)pentadecanoyl)oxy)-sn-glycero-3-phosphocholine, which belongs to the group of arsenic-containing phosphatidylcholines (AsPCs), recently discovered in herring caviar. The synthesized product will serve as a model compound to study biological and toxicological properties of arsenolipids in food.
Keywords:Arsenic  Arsenolipid  AsPC  Natural product
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