A novel strategy for the synthesis of 6H-chromeno [4, 3-b] quinoline by intramolecular Heck cyclization |
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| Authors: | Morteza Shiri Mina Fathollahi-Lahroud Zahra Yasaei |
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| Affiliation: | Department of Chemistry, Faculty of Physics and Chemistry, Alzahra University, Vanak, Tehran 1993893973, Iran |
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| Abstract: | A novel procedure for the synthesis of various derivatives of 6H-chromeno [4, 3-b] quinolines from intramolecular Heck reaction of 2-chloro-3-(phenoxymethyl) quinolines is described in this study. Intramolecular cyclization of N-alkylated indoles was efficiently investigated as well. The reaction is catalyzed by bis (triphenylphosphine) palladium (II) dichloride in acetonitrile at 80 °C. |
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| Keywords: | Intramolecular Heck reaction Palladium Indole |
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