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| Synthesis of the Natural Products Resveratrol (Ⅰ) and Isorhapotogenin (Ⅱ) | |
| 作者姓名： | Ya Bing FENG Lin WANG Zhi Zhong ZHAO |
| 作者单位： | Institute of Materia Medica，Chinese Academy of Medical Sciences Peking Union Medical Collage，Beijing，100050 |
| 摘 要： | ResveratrolIandisorhapotigeninIIaretwonaturalproductswithmanybiologicalactivities',andtheirtotalsynthesis'havebeenreported.LinMaoetal3flrstisolatedthemfromG.parvofOlium,atraditionalChineseherbusedtotreatrheumatoidarthritis,ulcerbleedingandbronchitis.Inanattempttopreparecnoughsamplesfortlirtherpharmacologicalevaluation,severalsynthesisstrategieshavebeenexplored'.WchavcdevelopedtwosyntheticapproachesofIandIIinSchemelandScheme2,respectivcly.Startingfrom3,5-dihydroxybenzoicacid,thecompound2wa… |
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