Synthesis of amine functionalized oxazolines with applications in asymmetric catalysis |
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Authors: | Jeremie J. Miller |
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Affiliation: | Department of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, UT 84112, United States |
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Abstract: | This paper describes the synthesis of three classes of amine functionalized oxazolines that have been successfully used in asymmetric catalysis in our laboratory. Failed synthetic routes and significantly improved procedures are discussed including the synthesis of ligands for Nozaki-Hiyama-Kishi (NHK) carbonyl allylation reactions that do not require chromatography for purification. |
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