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Ultrasonic-assisted synthesis of flavones by oxidative cyclization of 2′-hydroxychalcones using iodine monochloride
Institution:1. Department of Chemistry, Hakim Sabzevari University, Sabzevar, 96179-76487, Iran;2. Department of Chemistry, Tehran North Branch, Islamic Azad University, Tehran, Iran;3. Department of Chemistry, Payame Noor University (PNU), Tehran, 19395-4697, Iran;4. College of Chemistry, Shahrood University, Shahrood, 36155-316, Iran
Abstract:This paper presents an efficient methodology for the synthesis of flavones via the oxidative cyclization of 2′-hydroxychalcones in the presence of iodine monochloride with DMSO under ultrasound irradiation. Ultrasonic irradiation enhances the cyclization reaction and leads to reduced reaction time at lower reaction temperatures while generating flavones with high yields.
Keywords:2′-Hydroxychalcones  Flavones  Iodine monochloride  Ultrasonic irradiation  Oxidative cyclization
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