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A monolithic 180 nm CMOS dosimeter for wireless In Vivo Dosimetry
Affiliation:1. STFC Rutherford Appleton Laboratory, Particle Physics Dept., UK;2. Physics and Astronomy Dept. University of Bologna and INFN, Italy;3. Dept. of Electronic and Computer Engineering, Brunel University, UK;4. TowerJazz Semiconductor Ltd, Migdal Haemek, Israel and Technion, Haifa, Israel;5. CMRP, University of Wollongong, Australia;6. IIT, Istituto Italiano di Tecnologia, Politecnico di Torino, Italy;1. State Key Laboratory of Networking and Switching Technology, Beijing University of Posts and Telecommunications, Beijing 100876, China;2. School of Electronic and Information Engineering, Liaoning Technical University, Huludao 125105, China;3. State Key Laboratory of Computer Architecture, Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100190, China;1. Department of Safety, Health and Environmental Engineering, National Kaohsiung First University of Science and Technology, Kaohsiung 811, Taiwan;2. National Institute of Environmental Health Sciences, National Health Research Institutes, Miaoli 350, Taiwan;3. Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University College of Public Health, Taipei 100, Taiwan;4. Assisted Reproductive Technology Center, An-An Women and Children Clinic, Tainan 704, Taiwan;5. Department of Obstetrics and Gynecology, National Cheng Kung University Hospital, College of Medicine, Tainan 701, Taiwan;6. Department of Environmental and Occupational Medicine, National Taiwan University (NTU) and NTU Hospital, Taipei 100, Taiwan;1. Départment de physique nucleaire et corpusculaire, Université de Genève, 24 Quai E. Ansermet, Switzerland;2. ISDC, Observatoire de Genève, Université de Genève, Chemin d''Ecogia 16, 1290 Versoix, Switzerland;3. Instytut Fizyki Ja¸drowej im. H. Niewodniczańskiego Polskiej Akademii Nauk, ul. Radzikowskiego 152, 31-342 Kraków, Poland;4. Astronomical Observatory, University of Warsaw, Al. Ujazdowskie 4, 00-478 Warsaw, Poland;5. Astronomical Observatory, Jagiellonian University, ul. Orla 171, 30-244 Kraków, Poland;6. Centrum Badań Kosmicznych Polskiej Akademii Nauk, 18a Bartycka str., 00-716 Warsaw, Poland;7. Nicolaus Copernicus Astronomical Center, Polish Academy of Sciences, Warsaw, Poland;8. Astronomical Observatory, Taras Shevchenko National University of Kyiv, Observatorna str., 3, Kyiv, Ukraine;9. AGH University of Science and Technology, al. Mickiewicza 30, Kraków, Poland;10. Institute of Physics of the Czech Academy of Sciences, 17. listopadu 50, Olomouc & Na Slovance 2, Prague, Czech Republic;11. Department of Information Technologies, Jagiellonian University, ul. prof. Stanisława Łojasiewicza 11, 30-348 Kraków, Poland;12. Vrije Universiteit Brussels, Pleinlaan 2, 1050 Brussels, Belgium;13. Université Libre Bruxelles, Faculté des Sciences, Avenue Franklin Roosevelt 50, 1050 Brussels, Belgium
Abstract:The design, fabrication and testing of a novel monolithic system-on-chip dosimeter fabricated in a standard 180 nm CMOS technology is described. The device, implementing a radiation sensor and an RF transmitter, is proposed to address the need for real-time In Vivo Dosimetry (IVD) of radiation during Linac radiotherapy sessions. Owing to its small size, of approximately 1 mm3, such solution could be made in-body implantable and, as such, provide a much-enhanced high-resolution, real-time dose measurement to improve Quality Assurance (QA) in radiation therapy. The device transmits the related information on dose of radiation wirelessly to a remote receiver operating in the Medical Implant Communication Service (MICS) band. Comprehensive description of the various phases of this project, including the development of the radiation sensors and integrated RF transmitter to perform the readout, along with the final test results using a radiation beam, will be given.
Keywords:In vivo dosimetry  Floating gate  MICS  Wireless
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