Ultrasonic monitoring of droplets’ evaporation: Application to human whole blood |
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| Institution: | 1. University of Montpellier, IES, UMR 5214, F-34000 Montpellier, France;2. CNRS, IES, UMR 5214, F-34000 Montpellier, France;3. Aix-Marseille University, IUSTI, UMR CNRS 7343, France;1. Laboratory of Condensed Matter and Nanosciences, University of Monastir, 5019, Tunisia;2. Institut Néel, CNRS and Joseph Fourier university, B.P. 166, 38042 Grenoble, France;3. Institut Néel, CNRS et Université Joseph Fourier, BP 166, F-38042, Grenoble cedex 9, France;1. Tianjin Key Laboratory of Integrated Design and On-line Monitoring for Light Industry & Food Machinery and Equipment, College of Mechanical Engineering, Tianjin University of Science and Technology, 300222 Tianjin, China;2. International Science and Technology Cooperation Base of Low-Carbon Green Process Equipment, 300222 Tianjin, China;1. School of Mechanical Engineering, Xi’an Jiaotong University, Xi’an 710049, China;2. State Key Laboratory for Manufacturing Systems Engineering, Xi’an 710049, China;3. Key Laboratory of Education Ministry for Modern Design and Rotor-Bearing System, Xi’an 710049, China;1. Centre for Forensic Science, Department of Pure and Applied Chemistry, University of Strathclyde, United Kingdom;2. Forensic Services, Scottish Police Authority, United Kingdom;3. Wildlife DNA Forensics Unit, Science and Advice for Scottish Agriculture, Edinburgh, United Kingdom |
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| Abstract: | During a colloidal droplet evaporation, a sol–gel transition can be observed and is described by the desiccation time τD and the gelation time τG. These characteristic times, which can be linked to viscoelastic properties of the droplet and to its composition, are classically rated by analysis of mass droplet evolution during evaporation. Even if monitoring mass evolution versus time seems straightforward, this approach is very sensitive to environmental conditions (vibrations, air flow…) as mass has to be evaluated very accurately using ultra-sensitive weighing scales. In this study we investigated the potentialities of ultrasonic shear reflectometry to assess τD and τG in a simple and reliable manner. In order to validate this approach, our study has focused on blood droplets evaporation on which a great deal of work has recently been published. Desiccation and gelation times measured with shear ultrasonic reflectometry have been perfectly correlated to values obtained from mass versus time analysis. This ultrasonic method which is not very sensitive to environmental perturbations is therefore very interesting to monitor the drying of blood droplets in a simple manner and is more generally suitable for complex fluid droplets evaporation investigation. |
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| Keywords: | Ultrasound Shear waves Evaporation Droplets Human whole blood |
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