Recent advances in microfluidic production of Janus droplets and particles |
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| Institution: | 1. School of Chemical Engineering, Sichuan University, Chengdu 610065, China;2. State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China;3. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China;1. School of Nuclear Science and Technology, University of Science and Technology of China, Huang-Shan Road, Hefei, PR China;2. Sichuan Institute of Materials and Technology, 9, Hua-Feng Village, Jiangyou, PR China;3. Université de Strasbourg (UdS), Ecole de Chimie Polymères et Matériaux (ECPM), Charles Sadron Institute (ICS) – UPR 22 CNRS, Precision Macromolecular Chemistry Group (CMP), 23 rue du Loess, BP84047, 67034 Strasbourg Cedex 2, France;1. School of Nuclear Science and Technology, University of Science and Technology of China, Huang-Shan Road, He-Fei, PR China;2. Université de Strasbourg (UdS), Ecole de Chimie Polymères et Matériaux (ECPM), Institut de Chimie et Procédés pour l’Energie l’Environnement et la Santé (ICPEES) – UMR 7515 CNRS, Groupe d’Intensification et d’Intrégration des Procédés Polymères (G2IP), 25 rue Becquerel, F-67087 Strasbourg, France;1. MRL, Merck & Co., Inc., West Point, PA 19486, USA;2. MMD, Merck & Co., Inc., West Point, PA 19486, USA |
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| Abstract: | Microfluidic production of multicompartmental emulsion droplets and particles has received considerable attention of late. In particular, droplets having two physically and chemically distinct segments (so-called Janus droplets) and the anisotropic particles synthesized from these droplets, are becoming increasingly popular because of their novel and promising properties, which make them suitable for use in numerous applications, including for controlled drug release, display devices, and self-assembly. So far, a range of interesting anisotropies have been accorded to Janus droplets and particles via microfluidics; these span from chromatic, magnetic, and hydrophobic–hydrophilic characteristics to selective degradation properties. Here, we summarize and discuss the recent trends related to Janus droplets and particles produced through microfluidic processing. We also review the parallelization technologies being developed for scaling up microfluidic emulsification in the industry. |
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