Silyl modification of biologically active compounds. 3. organosilicon derivatives of aminoalcohols in the series of tetrahydroquinoline,tetrahydroisoquinoline, and tetrahydrosilaisoquinoline |
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Authors: | É. Lukevits I. Segal A. Zablotskaya S. Germane |
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Affiliation: | (1) Latvian Institute of Organic Synthesis, LV-1006 Riga |
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Abstract: | The N-(2-hydroxyethyl)-1, 2, 3, 4-tetrahydroquinoline, -isoquinoline, and -silaisoquinoline, and their trimethyland triethylsilyl derivatives and the corresponding methiodides were synthesized. The acute toxicity and psychotropic activity of the compounds synthesized were studied.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 793–799, June, 1996. Original article submitted April 25, 1996. |
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