| 手性2-甲基哌嗪的制备 |
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| 引用本文： | 刘博,杨春皓,谢毓元. 手性2-甲基哌嗪的制备[J]. 化学通报, 2006, 69(4): 247-251 |
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| 作者姓名： | 刘博 杨春皓 谢毓元 |
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| 作者单位： | 中国科学院上海药物研究所,上海,201203;中国科学院上海药物研究所,上海,201203;中国科学院上海药物研究所,上海,201203 |
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| 摘 要： | 手性2_甲基哌嗪在有机合成中有着广阔的应用前景。本文从手性试剂拆分、利用手性原料制备及构建手性中心等方面,对手性2_甲基哌嗪的制备过程进行了介绍并评价了各种路线的可行性和适用性。
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| 关 键 词： | 2-甲基哌嗪 手性 光学纯 制备 合成 |
| 收稿时间： | 2005-09-01 |
| 修稿时间： | 2005-09-012005-11-04 |
Preparation of Chiral 2-Methylpiperazine |
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| Liu Bo,Yang Chunhao,Xie Yuyuan. Preparation of Chiral 2-Methylpiperazine[J]. Chemistry, 2006, 69(4): 247-251 |
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| Authors: | Liu Bo Yang Chunhao Xie Yuyuan |
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| Affiliation: | Shanghai Institute of Materia Medica, Chinese Aeademy of Sciences, Shanghai 201203 |
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| Abstract: | Chiral 2-methylpiperazine was widely used in organic synthesis. In this paper, the preparation of chiral 2-methylpiperazine was introduced, including resolution with chiral reagent, synthesis from chiral material and building chiral centre. And the feasibility and fitness of the different routes were evaluated. |
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| Keywords: | 2-Methylpiperazine Chiral Enantiomerically pure Preparation Synthesis |
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