| Synthesis, Characterization and the Effect of Glucose-lowering of Guanidino Acid Oxovanadium（Ⅳ） Complexes |
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| 引用本文： | 刘巨涛,王晓红,李建新,刘景福.Synthesis, Characterization and the Effect of Glucose-lowering of Guanidino Acid Oxovanadium（Ⅳ） Complexes[J].中国化学,2004,22(7):761-763. |
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| 作者姓名： | 刘巨涛 王晓红 李建新 刘景福 |
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| 作者单位： | FacultyofChemistry,NortheastNormalUniversity,Changchun,Jilin130024,China |
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| 基金项目： | Project supported by the National Natural Science Foundation of China (No. 20171011). |
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| 摘 要： | Two guanidino acid oxovanadium(Ⅳ) complexes have been synthesized. Preliminary tests in vivo have shown that the two title complexes all display lowering glucose activity in vivo to STZ-rats. The effect of glucose-lowering of guanidino acetic acid oxovanadium(Ⅳ) complex in vivo is higher than that of guanidino propanoic acid oxovanadium(Ⅳ) complex.
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| 关 键 词： | 合成 葡萄糖活性 胍基乙酸 胍基丙酸 钒氧化物 |
Synthesis,characterization and the effect of glucose‐lowering of guanidino acid oxovanadium(IV) complexes |
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| LIU,Ju-Tao,a,b WANG,Xiao-Honga LI,Jian-Xina LIU,Jing-Fua aFaculty of Chemistry,Northeast Normal University,Changchun,Jilin ,China bKey Laboratory of Rare Earth Chemistry and Physics,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun,Jilin ,China.Synthesis,characterization and the effect of glucose‐lowering of guanidino acid oxovanadium(IV) complexes[J].Chinese Journal of Chemistry,2004,22(7):761-763. |
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| Authors: | LIU Ju-Tao a b WANG Xiao-Honga LI Jian-Xina LIU Jing-Fua aFaculty of Chemistry Northeast Normal University Changchun Jilin China bKey Laboratory of Rare Earth Chemistry and Physics Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun Jilin China |
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| Institution: | LIU,Ju-Tao*,a,b WANG,Xiao-Honga LI,Jian-Xina LIU,Jing-Fua aFaculty of Chemistry,Northeast Normal University,Changchun,Jilin 130024,China bKey Laboratory of Rare Earth Chemistry and Physics,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun,Jilin 130022,China |
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| Abstract: | Two guanidino acid oxovanadium(IV) complexes have been synthesized. Preliminary tests in vivo have shown that the two title complexes all display lowering glucose activity in vivo to STZ-rats. The effect of glucose-lowering of guanidino acetic acid oxovanadium(IV) complex in vivo is higher than that of guanidino propanoic acid oxovanadium(IV) complex. |
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| Keywords: | oxovanadium guanidino acetic acid guanidino propanoic acid lowering glucose activity |
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