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Unique CuI-pyridine based ligands catalytic systems for N-arylation of indoles and other heterocycles |
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| Authors: | Amol Taywade Snehal Chavan Avinash Ulhe |
| Institution: | 1. Department of Chemistry, Government Vidarbha Institute of Science and Humanities, Amravati, Maharashtra, India;2. Department of Chemistry, Mahatma Jyotiba Phule Educational Campus, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India |
| Abstract: | Two pyridine-based ligands (N-((pyridin-2-yl) methyl) pyridin-2-amine) L1 and (N-((pyridin-2-yl) methylene) pyridin-2-amine) L2 are explored in present work which are inexpensive, effective and environmentally benign in their properties. These have been utilized for C-N cross coupling reaction resulting in N-arylation. The N-arylation of indole, imidazole and triazole have been successfully carried out with different aryl and heteroaryl halides using these ligands. |
| Keywords: | C-N Cross coupling L1 (N-((pyridin-2-yl) methyl) pyridin-2-amine) L2 (N-((pyridin-2-yl) methylene) pyridin-2-amine) pyridine-based ligands-arylation |