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The Potentiometric Biosensor Acetylcholine Esterase as a Model System
Authors:Stephan Reher  Yvonne Lepka  Georg Schwedt
Institution:Technical University of Clausthal, Institute of Inorganic and Analytical Chemistry, Paul-Ernst-Stra?e 4, D-38678 Clausthal-Zellerfeld, Germany, DE
Abstract: In a methodical investigation of pH-detection systems (glass and polymer membrane electrodes and ion selective field effect transistor (ISFET)), the possible use of the acetylcholine esterase biosensor as a model for all pH-based biosensors is shown. It revealed that the biomembrane properties are more important for the result than the technology itself. All techniques resulted in a ΔH+ detection limit of 6*10−7 mol/L. Received January 20, 2001; accepted December 18, 2001; published online July 15, 2002
Keywords::   Biosensor  acetylcholine esterase  pH-glass electrode  polymer membrane electrode  ion selective field effect transistor  
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