Pyrimidones 1. Synthesis of some 1-substituted-5-aryl- and (4,5-diaryl)-2(1H)pyrimidones

A series of 1-substituted-5-aryl-2(1H)pyrimidones has been prepared by a method involving condensation of an appropriate N-substituted urea with either 2-aryl-3-(dimethylamino)-acroleins or 2-arylmalondialdehydes. On biological investigation, several compounds exhibited some antiinflammatory activity.