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Derivatives of 2,4-diamino-6-methylpteridine
Authors:John A Montgomery  James R Piper  Robert D Elliott  Eugene C Roberts  Carroll Temple  Y Fulmer Shealy
Abstract:Eighteen derivatives of 2,4-diamino-6-methylpteridine related to methotrexate and aminopterin have been prepared from 6-(bromomethyl)-2,4-pteridinediamine by nucleophilic displacement reactions. None of these compounds showed any antileukemic acitivity.
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