Fabrication of quantum dot-lectin conjugates as novel fluorescent probes for microscopic and flow cytometric identification of leukemia cells from normal lymphocytes |
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Authors: | Zhelev Zhivko Ohba Hideki Bakalova Rumiana Jose Rajan Fukuoka Satoshi Nagase Toshimi Ishikawa Mitsuru Baba Yoshinobu |
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Institution: | Single-Molecule Bioanalysis Laboratory, AIST-Shikoku, 2217-14, Hayashi-cho, Takamatsu, Kagawa-ken, Japan. |
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Abstract: | The present study describes a synthesis of QD-lectin conjugates and their application for identification of leukaemia cells from normal lymphocytes using fluorescent confocal microscopy and flow cytometry. The results are compared with commercially available FITC-lectin. |
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