A simple fluorometric assay for DNA exonuclease activity based on graphene oxide |
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Authors: | Lee Jieon Min Dal-Hee |
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Affiliation: | Department of Chemistry, Seoul National University, Gwanak-ro, Gwanak-gu, Seoul 151-747, Republic of Korea. |
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Abstract: | A new assay platform for DNA exonuclease activity is developed based on the preferential binding of single-stranded DNA (ssDNA) over double-stranded DNA (dsDNA) to graphene oxide. This approach allows a simple and quantitative activity measurement in a short time at low cost. |
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