Synthesis of HyBeacons and dual-labelled probes containing 2'-fluorescent groups for use in genetic analysis |
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| Authors: | Dobson Neil McDowell David G French David J Brown Lynda J Mellor John M Brown Tom |
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| Institution: | Department of Chemistry, University of Southampton, Highfield, Southampton, UK SO17 1BJ. |
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| Abstract: | An FMOC-protected 2'-hydroxyethyl uridine phosphoramidite has been used to synthesise fluorescein-labelled HyBeacon probes and "FAM-ROX" dual-labelled fluorogenic oligonucleotides. |
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