| Abstract: | Heating papaverine with chloral hydrate and benzoyl chloride formed products of the replacement of the hydrogen at the 15-C atom of papaverine: 15-(β-trichloro-α-hydroxyethyl)papaverine and 15-benzoylpapaverine. In reactions with monochloro- and trichloroacetic acids under mild conditions in the cold, salts at the nitrogen atom were formed: the monochloroacetate and the trichloroacetate. The products were characterized by the results of TLC (type KSK silica gel fixed with gypsum), elementary analyses, and IR and PMR spectroscopy. |
