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Tandem asymmetric conjugate addition-enolacetates formation of enantiomerically enriched zinc and aluminium enolates
Authors:Magali Vuagnoux-d&rsquo  Augustin
Affiliation:Department of Organic Chemistry, University of Geneva, 30, Quai Ernest Ansermet, 1211 Geneva 4, Switzerland
Abstract:The metal enolates, resulting from the copper-catalyzed enantioselective conjugate addition of organometallic reagents (Et2Zn or R3Al) to cyclic and acyclic enones are quantitatively trapped as enolacetates with acetic anhydride.
Keywords:Michael addition   Copper   Enolacetate
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