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A general and efficient CuI/BtH catalyzed coupling of aryl halides with thiols
Authors:Akhilesh Kumar Verma  Jaspal Singh  Ritu Chaudhary
Affiliation:Synthetic Organic Chemistry Research Laboratory, Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India
Abstract:We report an exceptionally mild, general and efficient copper catalyzed cross coupling reaction of aryl bromides and thiols using 0.5 mol % CuI and 1 mol % benzotriazole. Experimental simplicity, generality, functional group tolerance and low cost of the catalyst are advantages of the protocol.
Keywords:Benzotriazole   CuI   Aryl sulfide   C-S coupling   Aryl bromides
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