Dynamics of redox related elements (Fe,Co, Zn,and Se) and oxidative stress caused by Se-deficiency in rats |
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| Authors: | Y Sakuma K Matsuoka C Honda K Matsumoto K Endo |
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| Institution: | (1) Showa Pharmaceutical University, Higashi-Tamagawagakuen, Machida, Tokyo 194-8543, Japan;(2) Research Center for Charged Particle Therapy, National Institute of Radiological Science, 4-9-1 Anagawa, Inage-ku, Chiba-shi, Chiba 263-8555, Japan |
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| Abstract: | The dynamics of redox related elements (Fe, Co, Zn, and Se) were studied using instrumental neutron activation analysis as
a function of rat age in the range of 4 to 16 weeks. Activity levels of glutathione peroxidase (GSH-Px), thiobarbituric acid
reactive substance (TBARS) were assayed, and hydrogen peroxide (H2O2) concentrations were measured for the same liver homogenates using an X-band ESR spectrometer. The oxidative stress, the
aging effect, and the mineral valance are discussed. |
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