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| 基于罗丹明-B的双通道铜离子荧光探针及其活细胞的应用(英文) | |
| 引用本文： | 姜 李,张 波,孙 剑,尹 桂,尚通明,王 玲,王睿勇.基于罗丹明-B的双通道铜离子荧光探针及其活细胞的应用(英文)[J].无机化学学报,2010,26(10):1750-1755. |
| 作者姓名： | 姜 李 张 波 孙 剑 尹 桂 尚通明 王 玲 王睿勇 |
| 作者单位： | 1. 南京大学化学化工学院,南京,210093 2. 江苏技术师范学院,化学与环境工程学院,贵金属深加工技术及其应用实验室,常州,213001 3. 南京大学生命科学学院,南京,210093 |
| 摘 要： | 本文介绍了一种紫外-可见和荧光双通道铜离子探针,该探针基于罗丹明-B,通过水合肼为桥梁来连接三苯胺,便利而廉价。其在水体系下对铜离子显示出了良好的选择性和极高的灵敏度(2.78×10-8mol·L-1)。并且,通过初步的活细胞测试,表明该铜离子探针有着良好的生物相容性和细胞穿透性,在生物、医药领域有着非常大的潜力。 |
| 关 键 词： | 双通道 罗丹明 荧光 选择性和灵敏度 海拉细胞 |
Dual Channel Rhodamine Based Colorimetric Fluorescent Probe for Cu2+ in Living Cells |
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| JIANG Li,ZHANG Bo,SUN Jian,YIN Gui,SHANG Tong-Ming,WANG Ling and WANG Rui-Yong.Dual Channel Rhodamine Based Colorimetric Fluorescent Probe for Cu2+ in Living Cells[J].Chinese Journal of Inorganic Chemistry,2010,26(10):1750-1755. | |
| Authors: | JIANG Li ZHANG Bo SUN Jian YIN Gui SHANG Tong-Ming WANG Ling and WANG Rui-Yong |
| Institution: | School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093,School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093,School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093,School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093,School of Chemistry and Environmental Engineering, The Laboratory of Precious Metals Processing Technology and Application, Jiangsu Teachers University of Technology, Changzhou, Jiangsu 213001,School of Life Sciences, Nanjing University, Nanjing 210093 and School of Life Sciences, Nanjing University, Nanjing 210093 |
| Abstract: | An easy prepared fluorescence and UV-Vis dual channel probe for copper ion based on rhodamine-B, which exhibit high sensitivity (2.78x10-8 mol·L-1) and selectivity over other metal ions in mixed aqueous system (H2O:CH3CN=1:1 ,V/V), was developed and characterized. This probe involving rhodamine-B and triphenylamine together through the hydrazine bridge, could coordinate with Cu2+ and result in turn-on response in UV-Vis absorption and fluorescence. Furthermore, the cell stain experiments showed that compound 1 might be used for monitoring Cu2+ within biological samples. |
| Keywords: | dual channel rhodamine-B fluorescence sensitivity and selectivity heLa cells |
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