(1) Department of Health Sciences, Boston University, Boston, MA, USA;(2) InternationalUniversity of Bremen, Bremen, Germany;(3) University of Crete, Iraklion, Crete, Greece
Abstract:
Background
The neocortical commissures have a fundamental role in functional integration across the cerebral hemispheres. We investigated whether commissural projections in prefrontal cortices are organized according to the same or different rules as those within the same hemisphere, by quantitatively comparing density, topography, and laminar origin of contralateral and ipsilateral projections, labeled after unilateral injection of retrograde tracers in prefrontal areas.