DNA minor groove hydration probed with 4'-alkylated thymidines |
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Authors: | Detmer Ilka Summerer Daniel Marx Andreas |
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Affiliation: | Kekulé-Institut für Organische Chemie und Biochemie, Universit?t Bonn, Gerhard-Domagk-Str. 1, 53121 Bonn, Germany. |
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Abstract: | Employing modified oligonucleotides that are 4'-alkylated site-specifically we investigated the involvement of DNA minor groove hydration on DNA duplex stability and helix conformation. |
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