Purification and structure elucidation of two biologically active molecules from a new isolated <Emphasis Type="Italic">Streptomyces</Emphasis> sp. US 24 strain期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Purification and structure elucidation of two biologically active molecules from a new isolated Streptomyces sp. US 24 strain

Authors:	R. Mehdi-Ben Ameur L. Mellouli F. Chabchoub S. Fotso S. Bejar

Affiliation:	(1) Laboratory of Prokaryotic Enzymes and metabolites of the Centre of Biotechnology of Sfax, P.O. K, 3038 Sfax, Tunisia;(2) Laboratory of Applied Chemistry of the Faculty of Sciences of Sfax, University of Sfax, P.O. K, 3038 Tunisia;(3) Department of Organic Chemistry, University of Goettingen, Tammannstrasse 2, D-37077 Goettingen, Germany

Abstract:	Two compounds having biological activities, 3-indolethanol and (L-phe, L-pro) diketopiperazine, have been isolated from a new filamentous soil bacterium called Streptomyces sp. US24 strain.To our knowledge, it is the first time that these two active molecules are described from Streptomyces species. The structures of these two compounds were established on the basis on their spectral data such as IR, EI-MS, and ESI-MS spectrometry, as well as NMR 1D and 2D (COSY, HMQC, HMBC).Published in Khimiya Prirodnykh Soedinenii, No. 5, pp. 419–421, September–October, 2004.

Keywords:	Streptomyces sp. US 24 (L-phe, L-pro) diketopiperazine 3-indolethanol biological activities spectroscopic methods
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