A convergent synthesis of the C1-C16 segment of goniodomin A via palladium-catalyzed organostannane-thioester coupling |
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| Authors: | Fuwa Haruhiko Nakajima Motohiro Shi Jinglu Takeda Yoshiyuki Saito Tomoyuki Sasaki Makoto |
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| Institution: | Laboratory of Biostructural Chemistry, Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai, Japan. hfuwa@bios.tohoku.ac.jp |
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| Abstract: | A convergent synthesis of the C1-C16 segment of goniodomin A, an actin-targeting marine polyether macrolide natural product, has been achieved via a 2-fold application of palladium-catalyzed organostannane-thioester coupling. |
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