Synthesis of 5-benzyl-3-hydroxypyridine and its N-oxide |
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Authors: | V. S. Zhuravlev L. D. Smirnov V. P. Lezina K. M. Dyumaev |
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Affiliation: | (1) Institute of Chemical Physics, Academy of Sciences of the USSR, Moscow |
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Abstract: | Conclusions The acylation of benzene with 5-bromonicotinoyl chloride gave 5-bromo-3-benzoylpyridine in high yield, the Kizhner reduction of which led to the synthesis of 3-hydroxy-5-benzylpyridine in good yield.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No.1, pp.222–224, January, 1976.The authors thank N. M. Émanuél' for his constant interest in the work. |
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