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Cholinesterase inhibitory constituents from Onosma hispida
Authors:Ahmad Ijaz  Anis Itrat  Malik Abdul  Nawaz Sarfraz Ahmad  Choudhary Muhammad Iqbal
Institution:International Centre of Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Pakistan.
Abstract:Hispidone, a new flavanone, has been isolated from Onosma hispida and assigned the structure (2S)-5,2'-dihydroxy-7,4',5'-trimethoxyflavanone (1) by spectroscopic methods. In addition, (2S)-5,2'-dihydroxy-7,5'-dimethoxyflavanone (2), benzoic acid (3), and 4-hydroxy benzoic acid (4) are also reported for the first time from this species.
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