The influence of some triphenylantimony(V) catecholates and o‐amidophenolates on lipid peroxidation in vitro |
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| Authors: | Ivan V Smolyaninov Natalia A Antonova Andrey I Poddel'sky Viktoria P Osipova Nadezhda T Berberova Yuri T Pimenov |
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| Institution: | 1. Toxicology Research Group, Southern Ccientific Centre of the Russian Academy of Sciences, , 414025 Astrakhan, Russia;2. Astrakhan State Technical University, , 414025 Astrakhan, Russia;3. G. A. Razuvaev Institute of Organometallic Chemistry, Russian Academy of Sciences, , 603950 Nizhniy Novgorod, Russia |
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| Abstract: | A number of catecholates (complexes 1–3, 6) and o‐amidophenolates (complexes 4, 5) of triphenylantimony(V) was examined in the process of lipid peroxidation of liver homogenates and sperm of Russian sturgeon (Acipenser gueldenstaedti B.), and human red blood cells. It was shown that the influence of complexes 1–6 on lipid peroxidation process in model systems depends on the nature of redox‐active ligand and varies from weak anti‐ and pro‐oxidant (catecholates 1, 6) to pronounced antioxidant (catecholates and o‐amidophenolates 2–5). It was found that the complexes 2–5 are the more effective inhibitors of lipid peroxidation than standard antioxidant ionol. Copyright © 2012 John Wiley & Sons, Ltd. |
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| Keywords: | organoantimony redox‐active ligands lipid peroxidation TBARS |
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