An efficient Stille cross‐coupling reaction catalyzed by ortho‐palladated complex of tribenzylamine under microwave irradiation |
| |
| Authors: | Abdol R Hajipour Kazem Karami Fatemeh Rafiee |
| |
| Institution: | 1. Pharmaceutical Research Laboratory, Department of Chemistry, Isfahan University of Technology, , Isfahan, 84156 IR Iran;2. Department of Pharmacology, University of Wisconsin, Medical School, , Madison, 53706‐1532 WI, USA |
| |
| Abstract: | The catalytic activity of Pd{C6H4(CH2N(CH2Ph)2)}(μ‐Br)]2 complex as an efficient, stable and catalyst that is non‐sensitive to air and moisture was investigated in the Stille cross‐coupling reaction of various aryl halides with phenyltributyltins under microwave irradiation. The substituted biaryls were produced in excellent yield in short reaction times using a catalytic amount of this complex in DMF at 100 C. The combination of dimeric complex as homogeneous catalyst and microwave irradiation and also DMF as microwave‐active polar solvent gave higher yields in shorter reaction times. Copyright © 2011 John Wiley & Sons, Ltd. |
| |
| Keywords: | cyclopalladated catalyst tribenzylamine Stille reaction biaryls |
|
|
