PEG‐4000‐promoted palladium‐catalyzed N‐allylation in water: aminonaphthalene as an example |
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| Authors: | Chun‐Jen Shih Yi‐Jen Shue Shiang‐Yu Yang Shyh‐Chyun Yang |
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| Institution: | 1. School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, , Kaohsiung, 807 Taiwan;2. School of Medicine, College of Medicine, Kaohsiung Medical University, , Kaohsiung, 807 Taiwan |
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| Abstract: | An environmentally friendly, efficient catalytic process using palladium associated with ligands in a PEG4000–water system leading to N‐allylation was described in this study. PEG‐4000 was found to improve the palladium‐catalyzed allylic amination of allylic acetates with aminonaphthalenes and gave overall good to high yields of the corresponding N‐allylic aminonaphthalenes. Copyright © 2012 John Wiley & Sons, Ltd. |
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| Keywords: | palladium‐catalyzed allylation water aminonaphthalenes allylic acetates polyethylene glycols |
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