Synthesis of amides from imines using Et3SiH/Zn system |
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| Authors: | Mohammad Ghaffarzadeh Somaye Heidarifard Fereshteh Faraji Somaye Shahrivari Joghan |
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| Affiliation: | Chemistry and Chemical Engineering Research center of Iran (CCERCI), , Tehran, Iran |
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| Abstract: | A simple and efficient approach for the synthesis of amides by the reaction of imines and acyl chlorides in the presence of Et3SiH/Zn system in THF at ambient temperature is reported. Mild reaction conditions, good yields of products, short reaction time and operational simplicity are the advantages of this procedure. Copyright © 2012 John Wiley & Sons, Ltd. |
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| Keywords: | amide imine triethylsilane reduction fentanyl |
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