Optimization of the dopant for the trace determination of polycyclic aromatic hydrocarbons by liquid chromatography/dopant-assisted atmospheric-pressure photoionization/mass spectrometry |
| |
Authors: | Itoh Nobuyasu Aoyagi Yoshie Yarita Takashi |
| |
Affiliation: | National Metrology Institute of Japan, NMIJ, National Institute of Advanced Industrial Science and Technology, AIST, 1-1-1 Umezono, Tsukuba, Ibaraki 305-8563, Japan. nobuyasu-itoh@aist.go.jp |
| |
Abstract: | The composition of the dopant for the analysis of polycyclic aromatic hydrocarbons (PAHs) by liquid chromatography/dopant-assisted atmospheric-pressure photoionization/mass spectrometry under reversed-phase conditions was optimized to enhance the ionization efficiency for PAHs. The most suitable dopant was a toluene/anisole mixture (99.5:0.5, v/v) and it could improve limit of detections (LODs) to 0.79-168 ng mL(-1) (signal-to-noise (S/N)=3) for 16 common PAHs. The LODs are 3.8-40 times lower than those obtained with toluene alone and are comparable to those obtained using gas chromatography/mass spectrometry. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|