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Azaindole derivatives. 60. Nucleophilic substitution reactions in 6-chloro-5-azaindolines
Authors:V. A. Azimov  N. N. Bychikhina  L. N. Yakhontov
Affiliation:(1) S. Ordzhonikidze All-Union Scientific-Research Institute of Pharmaceutical Chemistry, 119021 Moscow
Abstract:Reactions involving nucleophilic substitution of the halogen atoms in 1-benzyl-6-chloro-7-cyano-5-azaindoline by alkoxy groups and residues of various amines were investigated. The effect of electron-acceptor substituents on the saponification of the alkoxy groups to give hydroxy groups is demonstrated. The effect of the character of the fusion of the pyridine and pyrrole rings on the ease of nucleophilic substitution is examined.See [1] for Communication 59.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1648–1653, December, 1981.
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