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Principles and applications of comprehensive two-dimensional gas chromatography
Affiliation:1. Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran;2. Engineering Faculty, Near East University, 99138, Nicosia, North Cyprus, Mersin 10, Turkey;3. Academic Center for Education, Culture and Research, East Azarbaijan, Tabriz, Iran;4. Pharmaceutical Analysis Research Center, Tabriz University of Medical Sciences, Tabriz, Iran;5. Food and Drug Safety Research Center, Tabriz University of Medical Sciences, Tabriz, Iran;1. VT MEMS Lab, Bradley Department of Electrical & Computer Engineering, Virginia Tech, Blacksburg, VA 24061, United States;2. Department of Civil and Environmental Engineering, Virginia Tech, Blacksburg, VA 24061, United States;3. SEPAC Lab, Bradley Department of Electrical & Computer Engineering, Virginia Tech, Blacksburg, VA 24061, United States;1. Gas Phase Separations Division, Agilent Technologies, 2850 Centerville Rd, Wilmington, DE 19808, USA;2. Normandie Univ, UNIROUEN, Laboratoire SMS-EA3233, 76130, Mont Saint Aignan, France;3. Laboratoire de Chromatographie Gazeuse, Total Research and Technology Gonfreville (TRTG), BP27, 76700 Harfleur, France;4. Dipartimento di Scienza e Tecnologia del Farmaco, Università di Torino, Via Pietro Giuria 9, I-10125 Torino, Italy
Abstract:This issue of Trends in Analytical Chemistry celebrates 50 years of gas chromatography (GC) — the greatest enabling technology for chemical analysis of volatile compounds. However, what may be considered the most powerful separation tool in GC — comprehensive two-dimensional gas chromatography (GC×GC) — is a development born of the 1990s. It was first described and almost fully established in the last decade of the twentieth century. The coming decades can be expected to see it flourish into a major operating mode of GC, when applications and fundamental principles will be further expanded, and, most importantly, its universal acceptance will be unquestioned. This article describes why the pioneers of GC×GC have so much faith in the new opportunities afforded by this exciting technology.
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