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Polylactide hollow spheres fabricated by interfacial polymerization in an oil-in-water emulsion system
Authors:Bingbing Jiang  Changyou Gao  Jiacong Shen
Institution:(1) Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, People’s Republic of China
Abstract:A one-step pathway has been adopted to fabricate biodegradable polylactide (PLA) hollow spheres by interfacial polymerization in an oil-in-water emulsion system. The mechanism of sphere formation is suggested with respect to interfacial cross-linking polymerization and subsequent precipitation of the unreacted PLA macromonomers onto the preformed shells. Their hollow nature and morphology were verified by transmission electron microscopy and scanning electron microscope characterizations.
Keywords:Biodegradable  Hollow spheres  Interfacial polymerization
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