| 环状“烯－二炔”抗癌抗菌素的研究进展 |
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| 引用本文： | 滕有为,郑朝晖,江绍开.环状“烯－二炔”抗癌抗菌素的研究进展[J].合成化学,1994(4). |
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| 作者姓名： | 滕有为 郑朝晖 江绍开 |
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| 作者单位： | 中国科学院成都有机化学研究所 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 新颖的环状“烯－二炔”抗癌抗菌素包括ｃａｌｉｃｈｅａｍｉｃｉｎｓ、ｅｓｐｅｒａｍｉｅｉｎｓ、ｄｙｎｅｍｉｃｉｎｓ、新制癌菌素发色团和ｋｅｄａｒｃｉｄｉｎ发色团。对这些抗癌抗菌素的发现、结构、生物活性、抗癌作用机制及合成研究进行了概述。参考文献８４篇。
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| 关 键 词： | Calicheamicin，Esperamicin，Dynemicin，烯－二炔，抗癌抗菌素 |
Progrere on the Research of the CyclicEnediyne Anticancer Antibioties |
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| Teng,You-Wei, Zheng,Zhao-Hui, Hiang,Shao-Kai,.Progrere on the Research of the CyclicEnediyne Anticancer Antibioties[J].Chinese Journal of Synthetic Chemistry,1994(4). |
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| Authors: | Teng You-Wei Zheng Zhao-Hui Hiang Shao-Kai |
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| Abstract: | The novel cyclic enediyne anticancer antibiotics include calicheamicins,esperamicins,dynemicins, neocarzinostatin chromophore and kedarcidin chromophore. We review the discovery,structure, biological activity , mechanisms of action and synthetic research of these anticancer antibi-oties. 84 referenas are presented. |
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| Keywords: | Calicheamicin Esperamicin Dynemicin Enediyne Anticancer antibiotics |
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