Two New Cucurbitane Triterpenoids from Immature Fruits of Momordica charantia |
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| Authors: | Zhen‐Jie Li Jian‐Chao Chen Yuan‐Yuan Deng Na‐Li Song Mu‐Yuan Yu Lin Zhou Ming‐Hua Qiu |
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| Institution: | 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, P.?R. China, (phone: +86‐871‐65223255;2. fax: +86‐871‐65223225);3. Key Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, P.?R. China;4. Yunnan Institute of Traditional Chinese Medicine and Materia Medica, Kunming 650223, P.?R. China |
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| Abstract: | Two new cucurbitane triterpenoids, kuguacin X ( 1 ) and kuguaglycoside I ( 2 ), together with three known analogs, were isolated from immature fruits of Momordica charantia. By detailed analysis of IR, NMR, and MS data, acid hydrolysis, and comparison with spectroscopic data of known compounds, the new compounds were determined to be (23E)‐5β,19‐epoxycucurbita‐6,23‐diene‐3β,22ξ,25‐triol ( 1 ) and (23E)‐5β,19‐epoxycucurbita‐6,23‐dien‐19‐on‐3β,25‐diol 3‐O‐β‐D ‐allopyranoside ( 2 ). |
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| Keywords: | Cucurbitane triterpenoids Kuguacin X Kuguaglycoside I Momordica charantia |
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