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Two New Eudesmanolides from the Flowers of Achillea millefolium
Authors:Chun‐Bao Zhang  Zhi‐Yu Ni  Jin Wang  Xia Qing  Hui‐Min Yan  Qing‐Wen Shi  Françoise Sauriol  Yu‐Cheng Gu  Yi‐Bing Wu
Institution:1. Department of Clinical Pharmacy, Harrison International Peace Hospital, No.?180 Renmin East Road, Hengshui 053000, P.?R. China;2. College of Basic Medicine, Hebei Key Laboratory of Forensic Medicine, Collaborative Innovation Center of Forensic Medical Molecular Identification, Hebei Medicinal University, 361 Zhongshan East Road, Shijiazhuang 050017, P.?R. China;3. Department of Pharmacology, Hebei Medical University, Shijiazhuang 050017, P.?R. China, (phone: +86‐311‐86265634);4. Department of Chemistry, Queen's University, Kingston, Ontario K7L 3N6, Canada;5. Syngenta, Jealott's Hill, International Research Centre, Berkshire, RG42 6EY, UK
Abstract:Two new eudesmanolides, 3β‐acetoxy‐1β,4α‐dihydroxy‐11αH‐eudesman‐12,6α‐olide ( 1 ) and 3β‐acetoxy‐1β‐hydroxy‐11αH‐eudesman‐4(15)‐en‐12,6α‐olide ( 2 ), were isolated from the flowers of Achillea millefolium, their structures were established on the basis of spectral analysis.
Keywords:Achillea millefolium  Eudesmanolides
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