Two New Triterpenoid Saponins from Stauntonia obovatifoliola Hayata ssp. intermedia |
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| Authors: | Xu‐Ran Lu Xiao‐Min Wang Zhi‐Min Wang Xiao‐Qing Chen Man‐Yuan Wang Mu‐Xin Gong |
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| Affiliation: | 1. Beijing Key Lab of TCM Collateral Disease Theory Research, School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, P.?R. China (phone: +86‐10‐83911632;2. fax: +86‐10‐83911638);3. Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, P.?R. China;4. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, P.?R. China |
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| Abstract: | Two new hederagenin‐type saponins, staunoside G ( 1 ) and staunoside H ( 2 ), along with twelve known triterpenoid saponins, were isolated from stems of Stauntonia obovatifoliola Hayata ssp. intermedia. Their structures were determined by analysis of HR‐EI‐MS, and 1D‐ and 2D‐NMR data, and comparison with those in literature. The two new compounds showed moderate cytotoxicities against three tumor cells, i.e., A549 (lung carcinoma), 4T1 (mammary carcinoma), and HeLa (cervical carcinoma). |
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| Keywords: | Stauntonia obovatifoliola Staunosides G and H Saponins Triterpenoid saponins Cytotoxic activity |
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