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Three New Phenyl Ether Derivatives from Aspergillus carneus HQ889708
Authors:Ping He  Sha‐Sha Tian  Yan Xu  He Yu  Yan‐Nan Ji  Hua‐Jie Zhu  Jian‐Heng Li
Institution:Chinese Center for Chirality, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmacy, Hebei University, Baoding 071002, P.?R. China, (phone/fax:+86‐0312‐5994812)
Abstract:Three new phenyl ether derivatives, 3‐hydroxy‐5‐(3‐hydroxy‐5‐methylphenoxy)benzoic acid ( 1 ), 3,4‐dihydroxy‐5‐(3‐hydroxy‐5‐methylphenoxy)benzoic acid ( 2 ), 3‐3‐hydroxy‐5‐(hydroxymethyl)phenoxy]‐5‐methylphenol ( 3 ), and three known compounds 4 – 6 were obtained from the fermentation broth of Aspergillus carneus HQ889708, which was isolated from sea water from South China Sea. The structures of compounds 1 – 3 were established on the basis of spectroscopic methods including ESI‐MS and NMR. Compounds 4 – 6 were reported before as synthesized products, herein, they are reported from nature for the first time.
Keywords:Aspergillus carneus  Phenyl ether derivatives  Solid fermentation
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